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High Cholesterol Diet Exacerbates Blood-Brain Barrier Disruption in LDLr–/– Mice: Impact on Cognitive Function

BACKGROUND: Evidence has revealed an association between familial hypercholesterolemia and cognitive impairment. In this regard, a connection between cognitive deficits and hippocampal blood-brain barrier (BBB) breakdown was found in low-density lipoprotein receptor knockout mice (LDLr–/–), a mouse...

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Detalles Bibliográficos
Autores principales:	de Oliveira, Jade, Engel, Daiane F., de Paula, Gabriela C., dos Santos, Danúbia B., Lopes, Jadna B., Farina, Marcelo, Moreira, Eduardo L.G., de Bem, Andreza F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683087/ https://www.ncbi.nlm.nih.gov/pubmed/32925052 http://dx.doi.org/10.3233/JAD-200541

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