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Neuronal Calcium Imaging, Excitability, and Plasticity Changes in the Aldh2(–)/(–) Mouse Model of Sporadic Alzheimer’s Disease

BACKGROUND: Dysregulated signaling in neurons and astrocytes participates in pathophysiological alterations seen in the Alzheimer’s disease brain, including increases in amyloid-β, hyperphosphorylated tau, inflammation, calcium dysregulation, and oxidative stress. These are often noted prior to the...

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Detalles Bibliográficos
Autores principales:	Ghoweri, Adam O., Gagolewicz, Peter, Frazier, Hilaree N., Gant, John C., Andrew, R. David, Bennett, Brian M., Thibault, Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683088/ https://www.ncbi.nlm.nih.gov/pubmed/32925058 http://dx.doi.org/10.3233/JAD-200617

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