Astrocytic TSPO Upregulation Appears Before Microglial TSPO in Alzheimer’s Disease

BACKGROUND: In vivo PET/SPECT imaging of neuroinflammation is primarily based on the estimation of the 18 kDa-translocator-protein (TSPO). However, TSPO is expressed by different cell types which complicates the interpretation. OBJECTIVE: The present study evaluates the cellular origin of TSPO alter...

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Detalles Bibliográficos
Autores principales: Tournier, Benjamin B., Tsartsalis, Stergios, Ceyzériat, Kelly, Fraser, Ben H., Grégoire, Marie-Claude, Kövari, Enikö, Millet, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683091/
https://www.ncbi.nlm.nih.gov/pubmed/32804124
http://dx.doi.org/10.3233/JAD-200136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683091/
https://www.ncbi.nlm.nih.gov/pubmed/32804124
http://dx.doi.org/10.3233/JAD-200136

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