Modeling α-Synucleinopathy in Organotypic Brain Slice Culture with Preformed α-Synuclein Amyloid Fibrils

BACKGROUND: Synucleinopathy is a group of neurodegenerative disorders characterized by neurodegeneration and accumulation of alpha-synuclein (α-syn) aggregates in various brain regions. The detailed mechanism of α-syn-caused neurotoxicity remains obscure, which is partly due to the lack of a suitabl...

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Detalles Bibliográficos
Autores principales: Roux, Amandine, Wang, Xinhe, Becker, Katelyn, Ma, Jiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683096/
https://www.ncbi.nlm.nih.gov/pubmed/32716318
http://dx.doi.org/10.3233/JPD-202026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683096/
https://www.ncbi.nlm.nih.gov/pubmed/32716318
http://dx.doi.org/10.3233/JPD-202026

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