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Envelope-Specific Adaptive Immunity following Transplantation of Hematopoietic Stem Cells Modified with VSV-G Lentivirus
Current approaches for hematopoietic stem cell gene therapy typically involve lentiviral gene transfer in tandem with a conditioning regimen to aid stem cell engraftment. Although many pseudotyped envelopes have the capacity to be immunogenic due to their viral origins, thus far immune responses aga...
Autores principales: | Rust, Blake J., Becker, Pamela S., Chandrasekaran, Devikha, Kubek, Sara P., Peterson, Christopher W., Adair, Jennifer E., Kiem, Hans-Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683283/ https://www.ncbi.nlm.nih.gov/pubmed/33294492 http://dx.doi.org/10.1016/j.omtm.2020.10.002 |
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