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Envelope-Specific Adaptive Immunity following Transplantation of Hematopoietic Stem Cells Modified with VSV-G Lentivirus

Current approaches for hematopoietic stem cell gene therapy typically involve lentiviral gene transfer in tandem with a conditioning regimen to aid stem cell engraftment. Although many pseudotyped envelopes have the capacity to be immunogenic due to their viral origins, thus far immune responses aga...

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Detalles Bibliográficos
Autores principales: Rust, Blake J., Becker, Pamela S., Chandrasekaran, Devikha, Kubek, Sara P., Peterson, Christopher W., Adair, Jennifer E., Kiem, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683283/
https://www.ncbi.nlm.nih.gov/pubmed/33294492
http://dx.doi.org/10.1016/j.omtm.2020.10.002

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