Utility of immunohistochemical staining for the diagnosis of Extra-adrenal mediastinal paraganglioma

Extra-adrenal, mediastinal paraganglioma are rare tumors that origin from sympathetic ganglia. Common diagnostic steps include CT, MRI and PET-Scan. We present a case where immunohistochemical staining was an essential step for final diagnosis in a patient without symptoms of endocrine activity and...

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Detalles Bibliográficos
Autores principales: Metelmann, Isabella B., Seyfarth, Hans-Jürgen, Schierle, Katrin, Kraemer, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683335/
https://www.ncbi.nlm.nih.gov/pubmed/33294355
http://dx.doi.org/10.1016/j.rmcr.2020.101278
Descripción
Sumario:Extra-adrenal, mediastinal paraganglioma are rare tumors that origin from sympathetic ganglia. Common diagnostic steps include CT, MRI and PET-Scan. We present a case where immunohistochemical staining was an essential step for final diagnosis in a patient without symptoms of endocrine activity and an uncommon location of this tumor entity. In combination with clinical particularities on the origin of the tumor and characteristic morphology, the immunohistochemical staining of tumor tissue is a necessary diagnostic tool for paraganglioma.

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