Utility of immunohistochemical staining for the diagnosis of Extra-adrenal mediastinal paraganglioma

Extra-adrenal, mediastinal paraganglioma are rare tumors that origin from sympathetic ganglia. Common diagnostic steps include CT, MRI and PET-Scan. We present a case where immunohistochemical staining was an essential step for final diagnosis in a patient without symptoms of endocrine activity and...

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Autores principales: Metelmann, Isabella B., Seyfarth, Hans-Jürgen, Schierle, Katrin, Kraemer, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683335/
https://www.ncbi.nlm.nih.gov/pubmed/33294355
http://dx.doi.org/10.1016/j.rmcr.2020.101278
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author Metelmann, Isabella B.
Seyfarth, Hans-Jürgen
Schierle, Katrin
Kraemer, Sebastian
author_facet Metelmann, Isabella B.
Seyfarth, Hans-Jürgen
Schierle, Katrin
Kraemer, Sebastian
author_sort Metelmann, Isabella B.
collection PubMed
description Extra-adrenal, mediastinal paraganglioma are rare tumors that origin from sympathetic ganglia. Common diagnostic steps include CT, MRI and PET-Scan. We present a case where immunohistochemical staining was an essential step for final diagnosis in a patient without symptoms of endocrine activity and an uncommon location of this tumor entity. In combination with clinical particularities on the origin of the tumor and characteristic morphology, the immunohistochemical staining of tumor tissue is a necessary diagnostic tool for paraganglioma.
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spelling pubmed-76833352020-12-07 Utility of immunohistochemical staining for the diagnosis of Extra-adrenal mediastinal paraganglioma Metelmann, Isabella B. Seyfarth, Hans-Jürgen Schierle, Katrin Kraemer, Sebastian Respir Med Case Rep Case Report Extra-adrenal, mediastinal paraganglioma are rare tumors that origin from sympathetic ganglia. Common diagnostic steps include CT, MRI and PET-Scan. We present a case where immunohistochemical staining was an essential step for final diagnosis in a patient without symptoms of endocrine activity and an uncommon location of this tumor entity. In combination with clinical particularities on the origin of the tumor and characteristic morphology, the immunohistochemical staining of tumor tissue is a necessary diagnostic tool for paraganglioma. Elsevier 2020-11-13 /pmc/articles/PMC7683335/ /pubmed/33294355 http://dx.doi.org/10.1016/j.rmcr.2020.101278 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Metelmann, Isabella B.
Seyfarth, Hans-Jürgen
Schierle, Katrin
Kraemer, Sebastian
Utility of immunohistochemical staining for the diagnosis of Extra-adrenal mediastinal paraganglioma
title Utility of immunohistochemical staining for the diagnosis of Extra-adrenal mediastinal paraganglioma
title_full Utility of immunohistochemical staining for the diagnosis of Extra-adrenal mediastinal paraganglioma
title_fullStr Utility of immunohistochemical staining for the diagnosis of Extra-adrenal mediastinal paraganglioma
title_full_unstemmed Utility of immunohistochemical staining for the diagnosis of Extra-adrenal mediastinal paraganglioma
title_short Utility of immunohistochemical staining for the diagnosis of Extra-adrenal mediastinal paraganglioma
title_sort utility of immunohistochemical staining for the diagnosis of extra-adrenal mediastinal paraganglioma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683335/
https://www.ncbi.nlm.nih.gov/pubmed/33294355
http://dx.doi.org/10.1016/j.rmcr.2020.101278
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