Cargando…

Early lung cancer diagnostic biomarker discovery by machine learning methods

Early diagnosis has been proved to improve survival rate of lung cancer patients. The availability of blood-based screening could increase early lung cancer patient uptake. Our present study attempted to discover Chinese patients’ plasma metabolites as diagnostic biomarkers for lung cancer. In this...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Ying, Meng, Wei-Yu, Li, Run-Ze, Wang, Yu-Wei, Qian, Xin, Chan, Chang, Yu, Zhi-Fang, Fan, Xing-Xing, Pan, Hu-Dan, Xie, Chun, Wu, Qi-Biao, Yan, Pei-Yu, Liu, Liang, Tang, Yi-Jun, Yao, Xiao-Jun, Wang, Mei-Fang, Leung, Elaine Lai-Han
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2020
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683339/ https://www.ncbi.nlm.nih.gov/pubmed/33217646 http://dx.doi.org/10.1016/j.tranon.2020.100907

Ejemplares similares

The key role of sphingolipid metabolism in cancer: New therapeutic targets, diagnostic and prognostic values, and anti-tumor immunotherapy resistance
por: Li, Run-Ze, et al.
Publicado: (2022)

Novel clinical biomarkers in blood and pleural effusion for diagnosing patients with tuberculosis distinguishing from malignant tumor
por: Wang, Jian, et al.
Publicado: (2022)

miR-20b promotes growth of non-small cell lung cancer through a positive feedback loop of the Wnt/β-catenin signaling pathway
por: Ren, Tao, et al.
Publicado: (2019)

Evodiamine suppresses non-small cell lung cancer by elevating CD8(+) T cells and downregulating the MUC1-C/PD-L1 axis
por: Jiang, Ze-Bo, et al.
Publicado: (2020)

Potential prognostic factors in progression-free survival for patients with cervical cancer
por: Chen, Hui-Hui, et al.
Publicado: (2021)

MicroRNA-421 confers paclitaxel resistance by binding to the KEAP1 3′UTR and predicts poor survival in non-small cell lung cancer
por: Duan, Fu-Gang, et al.
Publicado: (2019)

Identification of a New Potent Inhibitor Targeting KRAS in Non-small Cell Lung Cancer Cells
por: Xie, Chun, et al.
Publicado: (2017)

The Scientific Foundation of Chinese Herbal Medicine against COVID-19
por: Leung, Elaine Lai-Han, et al.
Publicado: (2020)

Detection of Single Cancer Cell Multidrug Resistance With Single Cell Bioanalyzer
por: Cai, Jun, et al.
Publicado: (2023)

Predictors and occurrence of postoperative cognitive dysfunction in children undergoing noncardiac surgery: A prospective cohort study
por: Han, Fang‐Fang, et al.
Publicado: (2022)

SCD1 is associated with tumor promotion, late stage and poor survival in lung adenocarcinoma
por: Huang, Jun, et al.
Publicado: (2016)

Current Clinical Progress of PD-1/PD-L1 Immunotherapy and Potential Combination Treatment in Non–Small Cell Lung Cancer
por: Li, Jia-Xin, et al.
Publicado: (2019)

Screening S protein – ACE2 blockers from natural products: Strategies and advances in the discovery of potential inhibitors of COVID-19
por: Ma, Le-le, et al.
Publicado: (2021)

Differential Expression Analysis Revealing CLCA1 to Be a Prognostic and Diagnostic Biomarker for Colorectal Cancer
por: Wei, Fang-Ze, et al.
Publicado: (2020)

Corrigendum: Differential Expression Analysis Revealing CLCA1 to Be a Prognostic and Diagnostic Biomarker for Colorectal Cancer
por: Wei, Fang-Ze, et al.
Publicado: (2020)

The Diagnostic Value of Serum L1CAM in Patients With Colorectal Cancer
por: Chu, Ling-Yu, et al.
Publicado: (2020)

New strategy for virus discovery: viruses identified in human feces in the last decade
por: Xie, GuangCheng, et al.
Publicado: (2013)

ROS-Responsive Berberine Polymeric Micelles Effectively Suppressed the Inflammation of Rheumatoid Arthritis by Targeting Mitochondria
por: Fan, Xing-xing, et al.
Publicado: (2020)

Honokiol Induces Apoptosis, G1 Arrest, and Autophagy in KRAS Mutant Lung Cancer Cells
por: Luo, Lian-Xiang, et al.
Publicado: (2017)

Targeting Mutant Kirsten Rat Sarcoma Viral Oncogene Homolog in Non-Small Cell Lung Cancer: Current Difficulties, Integrative Treatments and Future Perspectives
por: Li, Jia-Xin, et al.
Publicado: (2022)

Evaluation of the diagnostic performance of panfungal polymerase chain reaction assay in invasive fungal diseases
por: Cao, Guo-Jun, et al.
Publicado: (2017)

ILRC: a hybrid biomarker discovery algorithm based on improved L1 regularization and clustering in microarray data
por: Yu, Kun, et al.
Publicado: (2021)

Role of D‐dimer and Fibrinogen in the Diagnosis of Periprosthetic Joint Infection: A Systematic Review and Meta‐Analysis
por: Xu, Hong, et al.
Publicado: (2021)

Proscillaridin A induces apoptosis and suppresses non-small-cell lung cancer tumor growth via calcium-induced DR4 upregulation
por: Li, Run-Ze, et al.
Publicado: (2018)

The diagnostic value of electrocardiogram-based machine learning in long QT syndrome: a systematic review and meta-analysis
por: Wu, Min-Juan, et al.
Publicado: (2023)

Discovery of extracellular vesicle-delivered miR-185-5p in the plasma of patients as an indicator for advanced adenoma and colorectal cancer
por: Shi, Yun-Jie, et al.
Publicado: (2023)

Determination of the Volatile Constituents in Radix Flemingiae Philippinensis by GC–MS and a Heuristic Evolving Latent Projection Method
por: Xie, Jian-Wei, et al.
Publicado: (2010)

PA-MSHA induces inflamed tumor microenvironment and sensitizes tumor to anti-PD-1 therapy
por: Huang, Min, et al.
Publicado: (2022)

Differential analysis revealing APOC1 to be a diagnostic and prognostic marker for liver metastases of colorectal cancer
por: Shen, Hai-Yu, et al.
Publicado: (2021)

Discovery of a highly divergent hepadnavirus in shrews from China
por: Nie, Fang-Yuan, et al.
Publicado: (2019)

Methyl 2-[2-(tert-butoxycarbonylamino)-1,3-benzothiazole-6-carboxamido]acetate
por: Gao, Dan, et al.
Publicado: (2011)

Novel direct AMPK activator suppresses non-small cell lung cancer through inhibition of lipid metabolism
por: Chen, Xi, et al.
Publicado: (2017)

Exploring the common diagnostic gene KCNJ15 and shared pathway of ankylosing spondylitis and ulcerative colitis through integrated bioinformatics
por: Zhou, Su-Zhe, et al.
Publicado: (2023)

Current Applications of Machine Learning in Spine: From Clinical View
por: Ren, GuanRui, et al.
Publicado: (2021)

Immune checkpoints and immunotherapy in non-small cell lung cancer: Novel study progression, challenges and solutions
por: Ma, Lin-Rui, et al.
Publicado: (2021)

Low ligation has a lower anastomotic leakage rate after rectal cancer surgery
por: Chen, Jia-Nan, et al.
Publicado: (2020)

Discovery of novel inhibitors of RNA silencing suppressor P19 based on virtual screening
por: Hu, Fan, et al.
Publicado: (2018)

Molecular subtypes predict therapeutic responses and identifying and validating diagnostic signatures based on machine learning in chronic myeloid leukemia
por: Zhong, Fang-Min, et al.
Publicado: (2023)

Bitter-RF: A random forest machine model for recognizing bitter peptides
por: Zhang, Yu-Fei, et al.
Publicado: (2023)

Reduced beta2-glycoprotein I protects macrophages from ox-LDL-induced foam cell formation and cell apoptosis
por: Wang, Wei-Lin, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_nmfr273p7otjn1meep2iot4fqs