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Proglucagon-Derived Peptides Expression and Secretion in Rat Insulinoma INS-1 Cells
Rat insulinoma INS-1 cells are widely used to study insulin secretory mechanisms. Studies have shown that a population of INS-1 cells are bi-hormonal, co-expressing insulin, and proglucagon proteins. They coined this population as immature cells since they co-secrete proglucagon-derived peptides fro...
Autores principales: | Acosta-Montalvo, Ana, Saponaro, Chiara, Kerr-Conte, Julie, Prehn, Jochen H. M., Pattou, François, Bonner, Caroline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683504/ https://www.ncbi.nlm.nih.gov/pubmed/33240888 http://dx.doi.org/10.3389/fcell.2020.590763 |
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