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Quantitative proteomics reveal lineage-specific protein profiles in iPSC-derived Marfan syndrome smooth muscle cells

Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the FBN1 gene that produces wide disease phenotypic variability. The lack of ample genotype–phenotype correlation hinders translational study development aimed at improving disease prognosis. In response to this need, an in...

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Detalles Bibliográficos
Autores principales: Iosef, Cristiana, Pedroza, Albert J., Cui, Jason Z., Dalal, Alex R., Arakawa, Mamoru, Tashima, Yasushi, Koyano, Tiffany K., Burdon, Grayson, Churovich, Samantha M. P., Orrick, Joshua O., Pariani, Mitchel, Fischbein, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683538/
https://www.ncbi.nlm.nih.gov/pubmed/33230159
http://dx.doi.org/10.1038/s41598-020-77274-w