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Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes

Histone posttranslational modifications are key regulators of chromatin-associated processes including gene expression, DNA replication and DNA repair. Monoubiquitinated histone H2A, H2Aub (K118 in Drosophila or K119 in vertebrates) is catalyzed by the Polycomb group (PcG) repressive complex 1 (PRC1...

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Detalles Bibliográficos
Autores principales:	Barbour, Haithem, Daou, Salima, Hendzel, Michael, Affar, El Bachir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683540/ https://www.ncbi.nlm.nih.gov/pubmed/33230107 http://dx.doi.org/10.1038/s41467-020-19722-9

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