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Time-dynamic pulse modulation of spinal cord stimulation reduces mechanical hypersensitivity and spontaneous pain in rats

Enhancing the efficacy of spinal cord stimulation (SCS) is needed to alleviate the burden of chronic pain and dependence on opioids. Present SCS therapies are characterized by the delivery of constant stimulation in the form of trains of tonic pulses (TPs). We tested the hypothesis that modulated SC...

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Detalles Bibliográficos
Autores principales:	Edhi, Muhammad M., Heijmans, Lonne, Vanent, Kevin N., Bloye, Kiernan, Baanante, Amanda, Jeong, Ki-Soo, Leung, Jason, Zhu, Changfang, Esteller, Rosana, Saab, Carl Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683561/ https://www.ncbi.nlm.nih.gov/pubmed/33230202 http://dx.doi.org/10.1038/s41598-020-77212-w

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