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LILBID laser dissociation curves: a mass spectrometry-based method for the quantitative assessment of dsDNA binding affinities

One current goal in native mass spectrometry is the assignment of binding affinities to noncovalent complexes. Here we introduce a novel implementation of the existing laser-induced liquid bead ion desorption (LILBID) mass spectrometry method: this new method, LILBID laser dissociation curves, asses...

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Detalles Bibliográficos
Autores principales: Young, Phoebe, Hense, Genia, Immer, Carina, Wöhnert, Jens, Morgner, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683618/
https://www.ncbi.nlm.nih.gov/pubmed/33230224
http://dx.doi.org/10.1038/s41598-020-76867-9