Innovative use of magnetic resonance imaging-guided focused ultrasound surgery for non-invasive breast cancer: a report of two cases

OBJECTIVE: This report describes the first clinical experience with magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS) using the ExAblate 2100 system for non-invasive breast cancer. METHODS: Two women with non-invasive breast cancer underwent MRgFUS treatment. One week after the M...

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Detalles Bibliográficos
Autores principales: Matsutani, Akiko, Ide, Yoshimi, Miura, Sakiko, Takimoto, Masafumi, Amano, Sadao, Nakamura, Seigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683687/
https://www.ncbi.nlm.nih.gov/pubmed/33226529
http://dx.doi.org/10.1186/s40792-020-01032-3
Descripción
Sumario:OBJECTIVE: This report describes the first clinical experience with magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS) using the ExAblate 2100 system for non-invasive breast cancer. METHODS: Two women with non-invasive breast cancer underwent MRgFUS treatment. One week after the MRgFUS treatment, US-guided vacuum-assisted biopsy was performed for the ablated lesions at the same time as breast-conserving surgery. RESULTS: The patients experienced good cosmetic outcomes and did not experience any severe adverse events, such as skin burns. Pathological examination of the surgical specimens revealed a few degenerated intraductal lesions around the breast biopsy markers. CONCLUSION: Performing MRgFUS with the new ExAblate 2100 system appears to be safe and feasible. The histopathological results revealed that adequate ultrasound energy in the appropriate location can induce tumor necrosis.

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