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Innovative use of magnetic resonance imaging-guided focused ultrasound surgery for non-invasive breast cancer: a report of two cases

OBJECTIVE: This report describes the first clinical experience with magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS) using the ExAblate 2100 system for non-invasive breast cancer. METHODS: Two women with non-invasive breast cancer underwent MRgFUS treatment. One week after the M...

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Autores principales: Matsutani, Akiko, Ide, Yoshimi, Miura, Sakiko, Takimoto, Masafumi, Amano, Sadao, Nakamura, Seigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683687/
https://www.ncbi.nlm.nih.gov/pubmed/33226529
http://dx.doi.org/10.1186/s40792-020-01032-3
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author Matsutani, Akiko
Ide, Yoshimi
Miura, Sakiko
Takimoto, Masafumi
Amano, Sadao
Nakamura, Seigo
author_facet Matsutani, Akiko
Ide, Yoshimi
Miura, Sakiko
Takimoto, Masafumi
Amano, Sadao
Nakamura, Seigo
author_sort Matsutani, Akiko
collection PubMed
description OBJECTIVE: This report describes the first clinical experience with magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS) using the ExAblate 2100 system for non-invasive breast cancer. METHODS: Two women with non-invasive breast cancer underwent MRgFUS treatment. One week after the MRgFUS treatment, US-guided vacuum-assisted biopsy was performed for the ablated lesions at the same time as breast-conserving surgery. RESULTS: The patients experienced good cosmetic outcomes and did not experience any severe adverse events, such as skin burns. Pathological examination of the surgical specimens revealed a few degenerated intraductal lesions around the breast biopsy markers. CONCLUSION: Performing MRgFUS with the new ExAblate 2100 system appears to be safe and feasible. The histopathological results revealed that adequate ultrasound energy in the appropriate location can induce tumor necrosis.
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spelling pubmed-76836872020-11-27 Innovative use of magnetic resonance imaging-guided focused ultrasound surgery for non-invasive breast cancer: a report of two cases Matsutani, Akiko Ide, Yoshimi Miura, Sakiko Takimoto, Masafumi Amano, Sadao Nakamura, Seigo Surg Case Rep Case Report OBJECTIVE: This report describes the first clinical experience with magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS) using the ExAblate 2100 system for non-invasive breast cancer. METHODS: Two women with non-invasive breast cancer underwent MRgFUS treatment. One week after the MRgFUS treatment, US-guided vacuum-assisted biopsy was performed for the ablated lesions at the same time as breast-conserving surgery. RESULTS: The patients experienced good cosmetic outcomes and did not experience any severe adverse events, such as skin burns. Pathological examination of the surgical specimens revealed a few degenerated intraductal lesions around the breast biopsy markers. CONCLUSION: Performing MRgFUS with the new ExAblate 2100 system appears to be safe and feasible. The histopathological results revealed that adequate ultrasound energy in the appropriate location can induce tumor necrosis. Springer Berlin Heidelberg 2020-11-23 /pmc/articles/PMC7683687/ /pubmed/33226529 http://dx.doi.org/10.1186/s40792-020-01032-3 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Case Report
Matsutani, Akiko
Ide, Yoshimi
Miura, Sakiko
Takimoto, Masafumi
Amano, Sadao
Nakamura, Seigo
Innovative use of magnetic resonance imaging-guided focused ultrasound surgery for non-invasive breast cancer: a report of two cases
title Innovative use of magnetic resonance imaging-guided focused ultrasound surgery for non-invasive breast cancer: a report of two cases
title_full Innovative use of magnetic resonance imaging-guided focused ultrasound surgery for non-invasive breast cancer: a report of two cases
title_fullStr Innovative use of magnetic resonance imaging-guided focused ultrasound surgery for non-invasive breast cancer: a report of two cases
title_full_unstemmed Innovative use of magnetic resonance imaging-guided focused ultrasound surgery for non-invasive breast cancer: a report of two cases
title_short Innovative use of magnetic resonance imaging-guided focused ultrasound surgery for non-invasive breast cancer: a report of two cases
title_sort innovative use of magnetic resonance imaging-guided focused ultrasound surgery for non-invasive breast cancer: a report of two cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683687/
https://www.ncbi.nlm.nih.gov/pubmed/33226529
http://dx.doi.org/10.1186/s40792-020-01032-3
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