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Feed additives for the control of post-weaning Streptococcus suis disease and the effect on the faecal and nasal microbiota
Medicated feed is a common strategy to control the occurrence of Streptococcus suis disease in swine production, but feed additives may constitute an alternative to metaphylaxis. In a farm with post-weaning S. suis disease, the following additives were tested: lysozyme (Lys), medium chain fatty acid...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683732/ https://www.ncbi.nlm.nih.gov/pubmed/33230191 http://dx.doi.org/10.1038/s41598-020-77313-6 |
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author | Correa-Fiz, Florencia Neila-Ibáñez, Carlos López-Soria, Sergio Napp, Sebastian Martinez, Blanca Sobrevia, Laia Tibble, Simon Aragon, Virginia Migura-Garcia, Lourdes |
author_facet | Correa-Fiz, Florencia Neila-Ibáñez, Carlos López-Soria, Sergio Napp, Sebastian Martinez, Blanca Sobrevia, Laia Tibble, Simon Aragon, Virginia Migura-Garcia, Lourdes |
author_sort | Correa-Fiz, Florencia |
collection | PubMed |
description | Medicated feed is a common strategy to control the occurrence of Streptococcus suis disease in swine production, but feed additives may constitute an alternative to metaphylaxis. In a farm with post-weaning S. suis disease, the following additives were tested: lysozyme (Lys), medium chain fatty acids plus lysozyme (FA + Lys), FA plus a natural anti-inflammatory (FA + antiinf) and amoxicillin (Amox). During the course of the study, FA + antiinf and Amox groups showed lower prevalence of clinical signs compatible with S. suis disease than the rest of the groups. Piglets from the FA + antiinf group showed high diversity and richness in their nasal and faecal microbiota. Diet supplements did not have major effects on the faecal microbiota, where the genus Mitsuokella was the only differentially present in the FA + Lys group. In the nasal microbiota, piglets from FA + antiinf presented higher differential abundance of a sequence variant from Ruminococcaceae and lower abundance of an unclassified genus from Weeksellaceae. In general, we detected more significant changes in the nasal than in the feacal microbiota, and found that parity of the dams affected the microbiota composition of their offspring, with piglets born to gilts exhibiting lower richness and diversity. Our results suggest that additives could be useful to control post-weaning disease when removing antimicrobials in farms. |
format | Online Article Text |
id | pubmed-7683732 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-76837322020-11-24 Feed additives for the control of post-weaning Streptococcus suis disease and the effect on the faecal and nasal microbiota Correa-Fiz, Florencia Neila-Ibáñez, Carlos López-Soria, Sergio Napp, Sebastian Martinez, Blanca Sobrevia, Laia Tibble, Simon Aragon, Virginia Migura-Garcia, Lourdes Sci Rep Article Medicated feed is a common strategy to control the occurrence of Streptococcus suis disease in swine production, but feed additives may constitute an alternative to metaphylaxis. In a farm with post-weaning S. suis disease, the following additives were tested: lysozyme (Lys), medium chain fatty acids plus lysozyme (FA + Lys), FA plus a natural anti-inflammatory (FA + antiinf) and amoxicillin (Amox). During the course of the study, FA + antiinf and Amox groups showed lower prevalence of clinical signs compatible with S. suis disease than the rest of the groups. Piglets from the FA + antiinf group showed high diversity and richness in their nasal and faecal microbiota. Diet supplements did not have major effects on the faecal microbiota, where the genus Mitsuokella was the only differentially present in the FA + Lys group. In the nasal microbiota, piglets from FA + antiinf presented higher differential abundance of a sequence variant from Ruminococcaceae and lower abundance of an unclassified genus from Weeksellaceae. In general, we detected more significant changes in the nasal than in the feacal microbiota, and found that parity of the dams affected the microbiota composition of their offspring, with piglets born to gilts exhibiting lower richness and diversity. Our results suggest that additives could be useful to control post-weaning disease when removing antimicrobials in farms. Nature Publishing Group UK 2020-11-23 /pmc/articles/PMC7683732/ /pubmed/33230191 http://dx.doi.org/10.1038/s41598-020-77313-6 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Correa-Fiz, Florencia Neila-Ibáñez, Carlos López-Soria, Sergio Napp, Sebastian Martinez, Blanca Sobrevia, Laia Tibble, Simon Aragon, Virginia Migura-Garcia, Lourdes Feed additives for the control of post-weaning Streptococcus suis disease and the effect on the faecal and nasal microbiota |
title | Feed additives for the control of post-weaning Streptococcus suis disease and the effect on the faecal and nasal microbiota |
title_full | Feed additives for the control of post-weaning Streptococcus suis disease and the effect on the faecal and nasal microbiota |
title_fullStr | Feed additives for the control of post-weaning Streptococcus suis disease and the effect on the faecal and nasal microbiota |
title_full_unstemmed | Feed additives for the control of post-weaning Streptococcus suis disease and the effect on the faecal and nasal microbiota |
title_short | Feed additives for the control of post-weaning Streptococcus suis disease and the effect on the faecal and nasal microbiota |
title_sort | feed additives for the control of post-weaning streptococcus suis disease and the effect on the faecal and nasal microbiota |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683732/ https://www.ncbi.nlm.nih.gov/pubmed/33230191 http://dx.doi.org/10.1038/s41598-020-77313-6 |
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