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Pan-Cancer Analysis of the Mitophagy-Related Protein PINK1 as a Biomarker for the Immunological and Prognostic Role

INTRODUCTION: The PINK1 gene encodes a serine/threonine protein kinase that localizes to mitochondria and has usually been considered to protect cells from stress-induced mitochondrial dysfunction. PINK1 mutations have been observed to lead to autosomal recessive Parkinson’s disease. However, the im...

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Detalles Bibliográficos
Autores principales: Zhu, Lizhe, Wu, Wei, Jiang, Siyuan, Yu, Shibo, Yan, Yu, Wang, Ke, He, Jianjun, Ren, Yu, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683787/
https://www.ncbi.nlm.nih.gov/pubmed/33244455
http://dx.doi.org/10.3389/fonc.2020.569887