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Rejuveinix Shows a Favorable Clinical Safety Profile in Human Subjects and Exhibits Potent Preclinical Protective Activity in the Lipopolysaccharide-Galactosamine Mouse Model of Acute Respiratory Distress Syndrome and Multi‐Organ Failure
Background: New treatment platforms that can prevent acute respiratory distress syndrome (ARDS) or reduce its mortality rate in high-risk coronavirus disease 2019 (COVID-19) patients, such as those with an underlying cancer, are urgently needed. Rejuveinix (RJX) is an intravenous formulation of anti...
Autores principales: | Uckun, Fatih M., Carlson, James, Orhan, Cemal, Powell, Joy, Pizzimenti, Natalie M., van Wyk, Hendrik, Ozercan, Ibrahim H., Volk, Michael, Sahin, Kazim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683794/ https://www.ncbi.nlm.nih.gov/pubmed/33244300 http://dx.doi.org/10.3389/fphar.2020.594321 |
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