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Effect of external diaphragmatic pacing therapy on patients with chronic cor pulmonale: a randomized, controlled trial

OBJECTIVES: This study aimed to evaluate the effects of external diaphragmatic pacing (EDP) on patients with chronic cor pulmonale (CCP). METHODS: Fifty patients with CCP were enrolled in Kashgar Prefecture Second People’s Hospital in Xinjiang Uygur Autonomous Region of China from 2016 to 2017. The...

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Detalles Bibliográficos
Autores principales: Liu, Yongchao, Abula, Nuer Maimaiti, Wang, Qixing, Tong, Nana, Zhang, Xiangyu, Aisha, Aisikaer, Wang, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683919/
https://www.ncbi.nlm.nih.gov/pubmed/33208014
http://dx.doi.org/10.1177/0300060520965839
Descripción
Sumario:OBJECTIVES: This study aimed to evaluate the effects of external diaphragmatic pacing (EDP) on patients with chronic cor pulmonale (CCP). METHODS: Fifty patients with CCP were enrolled in Kashgar Prefecture Second People’s Hospital in Xinjiang Uygur Autonomous Region of China from 2016 to 2017. The patients were randomized into a group that received anti-CCP therapy (negative control group) or a group that received additional EDP treatment (EDP group). We recorded and compared maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), FEV1/FVC, and the 6-minute walking test between the two groups on the first and tenth days of treatment. RESULTS: Ten days after treatment began, MIP, FVC, and the 6-minute walking test were significantly improved in both groups. Importantly, MIP and FVC were significantly higher in the EDP group compared with the control group on the tenth day. CONCLUSION: In addition to treatment for CCP, these patients can obtain extra benefit by using EDP treatment.