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Synthesis, molecular docking, and in silico ADME/Tox profiling studies of new 1-aryl-5-(3-azidopropyl)indol-4-ones: Potential inhibitors of SARS CoV-2 main protease

The virus SARS CoV-2, which causes the respiratory infection COVID-19, continues its spread across the world and to date has caused more than a million deaths. Although COVID-19 vaccine development appears to be progressing rapidly, scientists continue the search for different therapeutic options to...

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Detalles Bibliográficos
Autores principales: Domínguez-Villa, Francisco Xavier, Durán-Iturbide, Noemi Angeles, Ávila-Zárraga, José Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683933/
https://www.ncbi.nlm.nih.gov/pubmed/33261847
http://dx.doi.org/10.1016/j.bioorg.2020.104497