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Outcomes of COVID-19: Disparities by ethnicity

OBJECTIVES: To investigate the role of ethnicity in COVID-19 outcome disparities in a cohort in Kuwait. METHODS: This is a retrospective analysis of 405 individuals infected with SARS-CoV-2 in Kuwait. Outcomes such as symptoms severity and mortality were considered. Multivariate logistic regression...

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Autores principales: Ali, Hamad, Alshukry, Abdullah, Marafie, Sulaiman K., AlRukhayes, Monera, Ali, Yaseen, Abbas, Mohammad Bu, Al-Taweel, Abdullah, Bukhamseen, Yousef, Dashti, Mohammad H., Al-Shammari, Abdullah A., Abu-Farha, Mohammad, AbuBakr, Jehad, Al-Mulla, Fahd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683943/
https://www.ncbi.nlm.nih.gov/pubmed/33246086
http://dx.doi.org/10.1016/j.meegid.2020.104639
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author Ali, Hamad
Alshukry, Abdullah
Marafie, Sulaiman K.
AlRukhayes, Monera
Ali, Yaseen
Abbas, Mohammad Bu
Al-Taweel, Abdullah
Bukhamseen, Yousef
Dashti, Mohammad H.
Al-Shammari, Abdullah A.
Abu-Farha, Mohammad
AbuBakr, Jehad
Al-Mulla, Fahd
author_facet Ali, Hamad
Alshukry, Abdullah
Marafie, Sulaiman K.
AlRukhayes, Monera
Ali, Yaseen
Abbas, Mohammad Bu
Al-Taweel, Abdullah
Bukhamseen, Yousef
Dashti, Mohammad H.
Al-Shammari, Abdullah A.
Abu-Farha, Mohammad
AbuBakr, Jehad
Al-Mulla, Fahd
author_sort Ali, Hamad
collection PubMed
description OBJECTIVES: To investigate the role of ethnicity in COVID-19 outcome disparities in a cohort in Kuwait. METHODS: This is a retrospective analysis of 405 individuals infected with SARS-CoV-2 in Kuwait. Outcomes such as symptoms severity and mortality were considered. Multivariate logistic regression models were used to report the odds ratios (OR) for ICU admission and dying from COVID-19. RESULTS: The cohort included 290 Arabs and 115 South Asians. South Asians recorded significantly higher COVID-19 death rates compared to Arabs (33% vs. 7.6%, P value<0.001). When compared to Arabs, South Asians also had higher odds of being admitted to the ICU (OR = 6.28, 95% CI: 3.34–11.80, p < 0.001). South Asian patients showed 7.62 (95% CI: 3.62–16.02, p < 0.001) times the odds of dying from COVID-19. CONCLUSION: COVID-19 patients with South Asians ethnicity in Kuwait are more likely to have worse prognosis and outcome when compared to patients with Arab ethnicity. This suggest a possible role for ethnicity in COVID-19 outcome disparities and this role is likely to be multifactorial.
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spelling pubmed-76839432020-11-24 Outcomes of COVID-19: Disparities by ethnicity Ali, Hamad Alshukry, Abdullah Marafie, Sulaiman K. AlRukhayes, Monera Ali, Yaseen Abbas, Mohammad Bu Al-Taweel, Abdullah Bukhamseen, Yousef Dashti, Mohammad H. Al-Shammari, Abdullah A. Abu-Farha, Mohammad AbuBakr, Jehad Al-Mulla, Fahd Infect Genet Evol Short Communication OBJECTIVES: To investigate the role of ethnicity in COVID-19 outcome disparities in a cohort in Kuwait. METHODS: This is a retrospective analysis of 405 individuals infected with SARS-CoV-2 in Kuwait. Outcomes such as symptoms severity and mortality were considered. Multivariate logistic regression models were used to report the odds ratios (OR) for ICU admission and dying from COVID-19. RESULTS: The cohort included 290 Arabs and 115 South Asians. South Asians recorded significantly higher COVID-19 death rates compared to Arabs (33% vs. 7.6%, P value<0.001). When compared to Arabs, South Asians also had higher odds of being admitted to the ICU (OR = 6.28, 95% CI: 3.34–11.80, p < 0.001). South Asian patients showed 7.62 (95% CI: 3.62–16.02, p < 0.001) times the odds of dying from COVID-19. CONCLUSION: COVID-19 patients with South Asians ethnicity in Kuwait are more likely to have worse prognosis and outcome when compared to patients with Arab ethnicity. This suggest a possible role for ethnicity in COVID-19 outcome disparities and this role is likely to be multifactorial. Elsevier B.V. 2021-01 2020-11-24 /pmc/articles/PMC7683943/ /pubmed/33246086 http://dx.doi.org/10.1016/j.meegid.2020.104639 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Communication
Ali, Hamad
Alshukry, Abdullah
Marafie, Sulaiman K.
AlRukhayes, Monera
Ali, Yaseen
Abbas, Mohammad Bu
Al-Taweel, Abdullah
Bukhamseen, Yousef
Dashti, Mohammad H.
Al-Shammari, Abdullah A.
Abu-Farha, Mohammad
AbuBakr, Jehad
Al-Mulla, Fahd
Outcomes of COVID-19: Disparities by ethnicity
title Outcomes of COVID-19: Disparities by ethnicity
title_full Outcomes of COVID-19: Disparities by ethnicity
title_fullStr Outcomes of COVID-19: Disparities by ethnicity
title_full_unstemmed Outcomes of COVID-19: Disparities by ethnicity
title_short Outcomes of COVID-19: Disparities by ethnicity
title_sort outcomes of covid-19: disparities by ethnicity
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683943/
https://www.ncbi.nlm.nih.gov/pubmed/33246086
http://dx.doi.org/10.1016/j.meegid.2020.104639
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