Cargando…
Model organism development and evaluation for late‐onset Alzheimer's disease: MODEL‐AD
Alzheimer's disease (AD) is a major cause of dementia, disability, and death in the elderly. Despite recent advances in our understanding of the basic biological mechanisms underlying AD, we do not know how to prevent it, nor do we have an approved disease‐modifying intervention. Both are essen...
Autores principales: | Oblak, Adrian L., Forner, Stefania, Territo, Paul R., Sasner, Michael, Carter, Gregory W., Howell, Gareth R., Sukoff‐Rizzo, Stacey J., Logsdon, Benjamin A., Mangravite, Lara M., Mortazavi, Ali, Baglietto‐Vargas, David, Green, Kim N., MacGregor, Grant R., Wood, Marcelo A., Tenner, Andrea J., LaFerla, Frank M., Lamb, Bruce T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683958/ https://www.ncbi.nlm.nih.gov/pubmed/33283040 http://dx.doi.org/10.1002/trc2.12110 |
Ejemplares similares
-
Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study
por: Oblak, Adrian L., et al.
Publicado: (2021) -
Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H
por: Kotredes, Kevin P., et al.
Publicado: (2021) -
Corrigendum: Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2(*)R47H
por: Kotredes, Kevin P., et al.
Publicado: (2022) -
Pharmacokinetic, pharmacodynamic, and transcriptomic analysis of chronic levetiracetam treatment in 5XFAD mice: A MODEL‐AD preclinical testing core study
por: Onos, Kristen D., et al.
Publicado: (2022) -
A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease
por: Preuss, Christoph, et al.
Publicado: (2020)