STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells

Alternative splicing (AS) is involved in cell fate decisions and embryonic development. However, regulation of these processes is poorly understood. Here, we have identified the serine threonine kinase receptor-associated protein (STRAP) as a putative spliceosome-associated factor. Upon Strap deleti...

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Detalles Bibliográficos
Autores principales: Jin, Lin, Chen, Yunjia, Crossman, David K., Datta, Arunima, Vu, Trung, Mobley, James A., Basu, Malay Kumar, Scarduzio, Mariangela, Wang, Hengbin, Chang, Chenbei, Datta, Pran K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684319/
https://www.ncbi.nlm.nih.gov/pubmed/33230114
http://dx.doi.org/10.1038/s41467-020-19698-6

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