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Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR

Rising numbers of cases of multidrug- and extensively drug-resistant Pseudomonas aeruginosa over recent years have created an urgent need for novel therapeutic approaches to cure potentially fatal infections. One such approach is virulence attenuation where anti-virulence compounds, designed to redu...

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Detalles Bibliográficos
Autores principales:	Grossman, Scott, Soukarieh, Fadi, Richardson, William, Liu, Ruiling, Mashabi, Alaa, Emsley, Jonas, Williams, Paul, Cámara, Miguel, Stocks, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editions Scientifiques Elsevier 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684530/ https://www.ncbi.nlm.nih.gov/pubmed/32927392 http://dx.doi.org/10.1016/j.ejmech.2020.112778

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