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A comparative UPLC‐Q‐Orbitrap‐MS untargeted metabolomics investigation of different parts of Clausena lansium (Lour.) Skeels

In this study, the non‐targeted large‐scale plant metabolomics (UPLC‐Q‐Orbitrap‐MS) was performed for the comparison of chemical profiling of the leaves, barks, flowers, peels, pulps, and seeds of Clausena lansium (Lour.) Skeels (called “wampee”). A total of 364 metabolites were identified, and 62 p...

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Detalles Bibliográficos
Autores principales: Fan, Ruiyi, Peng, Cheng, Zhang, Xinxin, Qiu, Diyang, Mao, Genlin, Lu, Yusheng, Zeng, Jiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684609/
https://www.ncbi.nlm.nih.gov/pubmed/33282233
http://dx.doi.org/10.1002/fsn3.1841
Descripción
Sumario:In this study, the non‐targeted large‐scale plant metabolomics (UPLC‐Q‐Orbitrap‐MS) was performed for the comparison of chemical profiling of the leaves, barks, flowers, peels, pulps, and seeds of Clausena lansium (Lour.) Skeels (called “wampee”). A total of 364 metabolites were identified, and 62 potential biomarkers were selected by the multivariate statistical analysis. Hierarchical cluster analysis suggested that the selected biomarkers were significant differential metabolites among various parts of wampee. Metabolic pathway analysis showed a significant enrichment of the “Flavone and flavonol synthesis” and “Isoquinoline alkaloid biosynthesis” pathway. This study provides important information for the isolation and identification of functional components from different tissues of wampee and the metabolic biosynthesis pathway elucidation in detail.