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Rho guanine nucleotide exchange factor 39 increases the viability, migration and invasion of clear cell renal cell carcinoma cells via the activation of the AKT/ERK signaling pathway

We attempted to explore the effect of Rho guanine nucleotide exchange factor 39 (ARHGEF39) on the phenotypes of clear cell renal cell carcinoma (ccRCC) cells and the underlying mechanism. Analyses of the data from The Cancer Genome Atlas (TCGA) illustrated that ARHGEF39 expression was upregulated in...

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Detalles Bibliográficos
Autores principales:	Wang, Shuzhong, Wang, Yanmei, Wang, Chuanyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Genética 2020
Materias:	Cellular, Molecular and Developmental Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684694/ https://www.ncbi.nlm.nih.gov/pubmed/33231603 http://dx.doi.org/10.1590/1678-4685-GMB-2019-0383

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