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Abdominal pain as first manifestation of lyme neuroborreliosis in children, case report and review of literature

BACKGROUND: Lyme neuroborreliosis can cause a variety of neurological manifestations. European children usually present facial nerve palsy, other cranial nerve palsies and aseptic meningitis. CASE PRESENTATION: We hereby report a case of Lyme neuroborreliosis in a 9-year-old boy with abdominal pain...

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Autores principales: Savasta, Salvatore, Fiorito, Ivan, Foiadelli, Thomas, Pichiecchio, Anna, Cambieri, Patrizia, Mariani, Bianca, Marone, Piero, Marseglia, Gianluigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684897/
https://www.ncbi.nlm.nih.gov/pubmed/33228741
http://dx.doi.org/10.1186/s13052-020-00936-y
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author Savasta, Salvatore
Fiorito, Ivan
Foiadelli, Thomas
Pichiecchio, Anna
Cambieri, Patrizia
Mariani, Bianca
Marone, Piero
Marseglia, Gianluigi
author_facet Savasta, Salvatore
Fiorito, Ivan
Foiadelli, Thomas
Pichiecchio, Anna
Cambieri, Patrizia
Mariani, Bianca
Marone, Piero
Marseglia, Gianluigi
author_sort Savasta, Salvatore
collection PubMed
description BACKGROUND: Lyme neuroborreliosis can cause a variety of neurological manifestations. European children usually present facial nerve palsy, other cranial nerve palsies and aseptic meningitis. CASE PRESENTATION: We hereby report a case of Lyme neuroborreliosis in a 9-year-old boy with abdominal pain as first symptom and subsequent onset of attention deficit and ataxia. Diagnosis was made by detection of specific antibody in both serum and cerebrospinal fluid with neuro-radiological images suggestive for this infectious disease. A 12-months follow-up was performed during which no relevant neurological sequelae were revealed. CONCLUSION: This case report shows that abdominal radiculitis, although extremely rare, could be the first manifestation of early Lyme neuroborreliosis in pediatric patients. Pediatricians must consider Lyme disease in the differential diagnosis of abdominal pain of unknown origin in children, especially in countries where the infection is endemic.
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spelling pubmed-76848972020-11-25 Abdominal pain as first manifestation of lyme neuroborreliosis in children, case report and review of literature Savasta, Salvatore Fiorito, Ivan Foiadelli, Thomas Pichiecchio, Anna Cambieri, Patrizia Mariani, Bianca Marone, Piero Marseglia, Gianluigi Ital J Pediatr Case Report BACKGROUND: Lyme neuroborreliosis can cause a variety of neurological manifestations. European children usually present facial nerve palsy, other cranial nerve palsies and aseptic meningitis. CASE PRESENTATION: We hereby report a case of Lyme neuroborreliosis in a 9-year-old boy with abdominal pain as first symptom and subsequent onset of attention deficit and ataxia. Diagnosis was made by detection of specific antibody in both serum and cerebrospinal fluid with neuro-radiological images suggestive for this infectious disease. A 12-months follow-up was performed during which no relevant neurological sequelae were revealed. CONCLUSION: This case report shows that abdominal radiculitis, although extremely rare, could be the first manifestation of early Lyme neuroborreliosis in pediatric patients. Pediatricians must consider Lyme disease in the differential diagnosis of abdominal pain of unknown origin in children, especially in countries where the infection is endemic. BioMed Central 2020-11-23 /pmc/articles/PMC7684897/ /pubmed/33228741 http://dx.doi.org/10.1186/s13052-020-00936-y Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Savasta, Salvatore
Fiorito, Ivan
Foiadelli, Thomas
Pichiecchio, Anna
Cambieri, Patrizia
Mariani, Bianca
Marone, Piero
Marseglia, Gianluigi
Abdominal pain as first manifestation of lyme neuroborreliosis in children, case report and review of literature
title Abdominal pain as first manifestation of lyme neuroborreliosis in children, case report and review of literature
title_full Abdominal pain as first manifestation of lyme neuroborreliosis in children, case report and review of literature
title_fullStr Abdominal pain as first manifestation of lyme neuroborreliosis in children, case report and review of literature
title_full_unstemmed Abdominal pain as first manifestation of lyme neuroborreliosis in children, case report and review of literature
title_short Abdominal pain as first manifestation of lyme neuroborreliosis in children, case report and review of literature
title_sort abdominal pain as first manifestation of lyme neuroborreliosis in children, case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684897/
https://www.ncbi.nlm.nih.gov/pubmed/33228741
http://dx.doi.org/10.1186/s13052-020-00936-y
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