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Endometriosis: A Clinicopathological Study in a Tertiary Care Hospital

Background  Endometriosis (EM) is an estrogen-dependent disease characterized by the presence of endometrial gland and stroma outside the uterus. It is commonly seen in the reproductive age group and is a leading cause of infertility. Patients present with chronic pelvic pain, menstrual abnormalitie...

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Autores principales: Bhat, Shubha P., Kaliyat, Sajitha, Laxminarayana, Kishan Prasad Hosapatna, Srinivas, Teerthanath, Venugopala, Krishna Prasad Holalkere, Shetty, Jayaprakash Kubalady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684995/
https://www.ncbi.nlm.nih.gov/pubmed/33268936
http://dx.doi.org/10.1055/s-0040-1720946
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author Bhat, Shubha P.
Kaliyat, Sajitha
Laxminarayana, Kishan Prasad Hosapatna
Srinivas, Teerthanath
Venugopala, Krishna Prasad Holalkere
Shetty, Jayaprakash Kubalady
author_facet Bhat, Shubha P.
Kaliyat, Sajitha
Laxminarayana, Kishan Prasad Hosapatna
Srinivas, Teerthanath
Venugopala, Krishna Prasad Holalkere
Shetty, Jayaprakash Kubalady
author_sort Bhat, Shubha P.
collection PubMed
description Background  Endometriosis (EM) is an estrogen-dependent disease characterized by the presence of endometrial gland and stroma outside the uterus. It is commonly seen in the reproductive age group and is a leading cause of infertility. Patients present with chronic pelvic pain, menstrual abnormalities, dyspareunia, or mass per abdomen. Surgical excision is the treatment of choice with postoperative medications and progesterone agents. Aims and Objectives  This study aims at determining the distribution of EM in terms of age, parity, symptoms, site, morphological features. We also analyzed the management of EM in these cases. Methodology  This is a retrospective study done in a tertiary care hospital in Mangalore, India. The case records of 77 histopathologically confirmed cases of EM during the 7 years between June 2012 and May 2019 were studied. Demographic profiles, parity, presenting complaints, site of the lesion, morphological features, treatment given, follow-up, and recurrence were noted and analyzed. Results  Of the 77 patients with EM, the most common age group was the fourth decade (40%). The majority (31, 40.25%) of the patients in this study were nulliparous. Chronic pelvic pain was the most common symptom. The most frequent site was ovary. Conclusion  The most frequent site of EM is ovary, leading to infertility. With the advent of laparoscopy, early diagnosis and excision have been feasible. The histopathological examination should be done for confirmation. Awareness of this disease among health care professionals is necessary whenever a woman in reproductive age presents with chronic pelvic pain and infertility.
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spelling pubmed-76849952020-12-01 Endometriosis: A Clinicopathological Study in a Tertiary Care Hospital Bhat, Shubha P. Kaliyat, Sajitha Laxminarayana, Kishan Prasad Hosapatna Srinivas, Teerthanath Venugopala, Krishna Prasad Holalkere Shetty, Jayaprakash Kubalady J Lab Physicians Background  Endometriosis (EM) is an estrogen-dependent disease characterized by the presence of endometrial gland and stroma outside the uterus. It is commonly seen in the reproductive age group and is a leading cause of infertility. Patients present with chronic pelvic pain, menstrual abnormalities, dyspareunia, or mass per abdomen. Surgical excision is the treatment of choice with postoperative medications and progesterone agents. Aims and Objectives  This study aims at determining the distribution of EM in terms of age, parity, symptoms, site, morphological features. We also analyzed the management of EM in these cases. Methodology  This is a retrospective study done in a tertiary care hospital in Mangalore, India. The case records of 77 histopathologically confirmed cases of EM during the 7 years between June 2012 and May 2019 were studied. Demographic profiles, parity, presenting complaints, site of the lesion, morphological features, treatment given, follow-up, and recurrence were noted and analyzed. Results  Of the 77 patients with EM, the most common age group was the fourth decade (40%). The majority (31, 40.25%) of the patients in this study were nulliparous. Chronic pelvic pain was the most common symptom. The most frequent site was ovary. Conclusion  The most frequent site of EM is ovary, leading to infertility. With the advent of laparoscopy, early diagnosis and excision have been feasible. The histopathological examination should be done for confirmation. Awareness of this disease among health care professionals is necessary whenever a woman in reproductive age presents with chronic pelvic pain and infertility. Thieme Medical and Scientific Publishers Pvt. Ltd. 2020-12 2020-11-23 /pmc/articles/PMC7684995/ /pubmed/33268936 http://dx.doi.org/10.1055/s-0040-1720946 Text en The Indian Association of Laboratory Physicians. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.) https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Bhat, Shubha P.
Kaliyat, Sajitha
Laxminarayana, Kishan Prasad Hosapatna
Srinivas, Teerthanath
Venugopala, Krishna Prasad Holalkere
Shetty, Jayaprakash Kubalady
Endometriosis: A Clinicopathological Study in a Tertiary Care Hospital
title Endometriosis: A Clinicopathological Study in a Tertiary Care Hospital
title_full Endometriosis: A Clinicopathological Study in a Tertiary Care Hospital
title_fullStr Endometriosis: A Clinicopathological Study in a Tertiary Care Hospital
title_full_unstemmed Endometriosis: A Clinicopathological Study in a Tertiary Care Hospital
title_short Endometriosis: A Clinicopathological Study in a Tertiary Care Hospital
title_sort endometriosis: a clinicopathological study in a tertiary care hospital
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684995/
https://www.ncbi.nlm.nih.gov/pubmed/33268936
http://dx.doi.org/10.1055/s-0040-1720946
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