Notch3 Knockout Suppresses Mouse Mammary Gland Development and Inhibits the Proliferation of 4T1 Murine Mammary Carcinoma Cells via CCL2/CCR4 Axis

Our previous study found that Notch3 knockout mice exhibit defects in mammary gland development. To elucidate the underlying mechanism, tissue samples were subjected to RNA-seq, GO, and KEGG enrichment analyses and qRT-PCR validation. Of enriched pathways, chemokine signaling pathway and cytokine–cy...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Wei, Tan, Junyu, Guo, Yuxian, Chen, Shuzhao, Fan, Liping, Li, Yaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685216/
https://www.ncbi.nlm.nih.gov/pubmed/33244467
http://dx.doi.org/10.3389/fcell.2020.594372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685216/
https://www.ncbi.nlm.nih.gov/pubmed/33244467
http://dx.doi.org/10.3389/fcell.2020.594372

Ejemplares similares