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Notch family members follow stringent requirements for intracellular domain dimerization at sequence-paired sites

Notch signaling is essential for multicellular life, regulating core functions such as cellular identity, differentiation, and fate. These processes require highly sensitive systems to avoid going awry, and one such regulatory mechanism is through Notch intracellular domain dimerization. Select Notc...

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Detalles Bibliográficos
Autores principales: Crow, Jacob J., Albig, Allan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685452/
https://www.ncbi.nlm.nih.gov/pubmed/33232323
http://dx.doi.org/10.1371/journal.pone.0234101