CYLD-mutant cylindroma-like basaloid carcinoma of the anus: a genetically and morphologically distinct class of HPV-related anal carcinoma

Rare reports of anal carcinoma (AC) describe histologic resemblance to cutaneous cylindroma, but mutations in the tumor suppressor CYLD, the gene responsible for familial and sporadic cylindromas, have not been systematically investigated in AC. Here, we investigate CYLD-mutant AC, focusing on molec...

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Detalles Bibliográficos
Autores principales: Williams, Erik A., Montesion, Meagan, Sharaf, Radwa, Corines, James, Patel, Parth J., Gillespie, Brendan J., Pavlick, Dean C., Sokol, Ethan S., Alexander, Brian M., Williams, Kevin Jon, Elvin, Julia A., Ross, Jeffrey S., Ramkissoon, Shakti H., Hemmerich, Amanda C., Tse, Julie Y., Mochel, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685972/
https://www.ncbi.nlm.nih.gov/pubmed/32461623
http://dx.doi.org/10.1038/s41379-020-0584-2

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