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Off-the-Shelf Allogeneic T Cell Therapies for Cancer: Opportunities and Challenges Using Naturally Occurring “Universal” Donor T Cells

Chimeric antigen receptor (CAR) engineered T cell therapies individually prepared for each patient with autologous T cells have recently changed clinical practice in the management of B cell malignancies. Even though CARs used to redirect polyclonal T cells to the tumor are not HLA restricted, CAR T...

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Detalles Bibliográficos
Autores principales:	Perez, Cynthia, Gruber, Isabelle, Arber, Caroline
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685996/ https://www.ncbi.nlm.nih.gov/pubmed/33262761 http://dx.doi.org/10.3389/fimmu.2020.583716

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