Targeting T cell oxidative metabolism to improve influenza survival in a mouse model of obesity

BACKGROUND: Obesity is associated with impaired primary and secondary immune responses to influenza infection, with T cells playing a critical role. T cell function is highly influenced by the cellular metabolic state; however, it remains unknown how altered systemic metabolism in obesity alters T c...

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Detalles Bibliográficos
Autores principales: Alwarawrah, Yazan, Nichols, Amanda G., Green, William D., Eisner, William, Kiernan, Kaitlin, Warren, Jonathan, Hale, Laura P., Beck, Melinda A., MacIver, Nancie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686301/
https://www.ncbi.nlm.nih.gov/pubmed/33037327
http://dx.doi.org/10.1038/s41366-020-00692-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686301/
https://www.ncbi.nlm.nih.gov/pubmed/33037327
http://dx.doi.org/10.1038/s41366-020-00692-3

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