Cargando…
Targeting T cell oxidative metabolism to improve influenza survival in a mouse model of obesity
BACKGROUND: Obesity is associated with impaired primary and secondary immune responses to influenza infection, with T cells playing a critical role. T cell function is highly influenced by the cellular metabolic state; however, it remains unknown how altered systemic metabolism in obesity alters T c...
Autores principales: | Alwarawrah, Yazan, Nichols, Amanda G., Green, William D., Eisner, William, Kiernan, Kaitlin, Warren, Jonathan, Hale, Laura P., Beck, Melinda A., MacIver, Nancie J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686301/ https://www.ncbi.nlm.nih.gov/pubmed/33037327 http://dx.doi.org/10.1038/s41366-020-00692-3 |
Ejemplares similares
-
OR12-2 Obesity Induces Changes in T Cell Metabolism and Function
por: Alwarawrah, Yazan, et al.
Publicado: (2019) -
Effects of T cell leptin signaling on systemic glucose tolerance and T cell responses in obesity
por: Kiernan, Kaitlin, et al.
Publicado: (2023) -
Changes in Nutritional Status Impact Immune Cell Metabolism and Function
por: Alwarawrah, Yazan, et al.
Publicado: (2018) -
SUN-649 Metabolic and Functional Regulation of T Cells by Insulin and Insulin like Growth Factor 1
por: Kiernan, Kaitlin, et al.
Publicado: (2020) -
The Role of the Adipokine Leptin in Immune Cell Function in Health and Disease
por: Kiernan, Kaitlin, et al.
Publicado: (2021)