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Multiple gene substitution by Target-AID base-editing technology in tomato
The use of Target activation-induced cytidine deaminase (Target-AID) base-editing technology with the CRISPR-Cas 9 system fused with activation-induced cytidine deaminase (AID) resulted in the substitution of a cytidine with a thymine. In previous experiments focusing on a single target gene, this s...
Autores principales: | Hunziker, Johan, Nishida, Keiji, Kondo, Akihiko, Kishimoto, Sanae, Ariizumi, Tohru, Ezura, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686336/ https://www.ncbi.nlm.nih.gov/pubmed/33235312 http://dx.doi.org/10.1038/s41598-020-77379-2 |
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