Manipulation of Autophagy and Apoptosis Facilitates Intracellular Survival of Staphylococcus aureus in Human Neutrophils

Polymorphonuclear neutrophils (PMN) are critical for first line innate immune defence against Staphylococcus aureus. Mature circulating PMN maintain a short half-life ending in constitutive apoptotic cell death. This makes them unlikely candidates as a bacterial intracellular niche. However, there i...

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Detalles Bibliográficos
Autores principales: Mulcahy, Michelle E., O’Brien, Eóin C., O’Keeffe, Kate M., Vozza, Emilio G., Leddy, Neal, McLoughlin, Rachel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686353/
https://www.ncbi.nlm.nih.gov/pubmed/33262756
http://dx.doi.org/10.3389/fimmu.2020.565545

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