Identification and validation of 174 COVID-19 vaccine candidate epitopes reveals low performance of common epitope prediction tools

The outbreak of SARS-CoV-2 (2019-nCoV) virus has highlighted the need for fast and efficacious vaccine development. Stimulation of a proper immune response that leads to protection is highly dependent on presentation of epitopes to circulating T-cells via the HLA complex. SARS-CoV-2 is a large RNA v...

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Detalles Bibliográficos
Autores principales: Prachar, Marek, Justesen, Sune, Steen-Jensen, Daniel Bisgaard, Thorgrimsen, Stephan, Jurgons, Erik, Winther, Ole, Bagger, Frederik Otzen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686376/
https://www.ncbi.nlm.nih.gov/pubmed/33235258
http://dx.doi.org/10.1038/s41598-020-77466-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686376/
https://www.ncbi.nlm.nih.gov/pubmed/33235258
http://dx.doi.org/10.1038/s41598-020-77466-4

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