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Identification and validation of 174 COVID-19 vaccine candidate epitopes reveals low performance of common epitope prediction tools
The outbreak of SARS-CoV-2 (2019-nCoV) virus has highlighted the need for fast and efficacious vaccine development. Stimulation of a proper immune response that leads to protection is highly dependent on presentation of epitopes to circulating T-cells via the HLA complex. SARS-CoV-2 is a large RNA v...
Autores principales: | Prachar, Marek, Justesen, Sune, Steen-Jensen, Daniel Bisgaard, Thorgrimsen, Stephan, Jurgons, Erik, Winther, Ole, Bagger, Frederik Otzen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686376/ https://www.ncbi.nlm.nih.gov/pubmed/33235258 http://dx.doi.org/10.1038/s41598-020-77466-4 |
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