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Bioassay-based Corchorus capsularis L. leaf-derived β-sitosterol exerts antileishmanial effects against Leishmania donovani by targeting trypanothione reductase

Leishmaniasis, a major neglected tropical disease, affects millions of individuals worldwide. Among the various clinical forms, visceral leishmaniasis (VL) is the deadliest. Current antileishmanial drugs exhibit toxicity- and resistance-related issues. Therefore, advanced chemotherapeutic alternativ...

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Detalles Bibliográficos
Autores principales: Pramanik, Pijush Kanti, Chakraborti, Sajal, Bagchi, Angshuman, Chakraborti, Tapati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686382/
https://www.ncbi.nlm.nih.gov/pubmed/33235245
http://dx.doi.org/10.1038/s41598-020-77066-2