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Intracellular A53T Mutant α-Synuclein Impairs Adult Hippocampal Newborn Neuron Integration
Dendritic dysfunction is an early event in α-synuclein (α-syn) mediated neurodegeneration. Altered postsynaptic potential and loss of dendritic spines have been observed in different in vitro and in vivo models of synucleinopathies. The integration of newborn neurons into the hippocampus offers the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686440/ https://www.ncbi.nlm.nih.gov/pubmed/33262984 http://dx.doi.org/10.3389/fcell.2020.561963 |