Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR

Epigenetic differences may help to distinguish between PTSD cases and trauma-exposed controls. Here, we describe the results of the largest DNA methylation meta-analysis of PTSD to date. Ten cohorts, military and civilian, contribute blood-derived DNA methylation data from 1,896 PTSD cases and traum...

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Detalles Bibliográficos
Autores principales: Smith, Alicia K., Ratanatharathorn, Andrew, Maihofer, Adam X., Naviaux, Robert K., Aiello, Allison E., Amstadter, Ananda B., Ashley-Koch, Allison E., Baker, Dewleen G., Beckham, Jean C., Boks, Marco P., Bromet, Evelyn, Dennis, Michelle, Galea, Sandro, Garrett, Melanie E., Geuze, Elbert, Guffanti, Guia, Hauser, Michael A., Katrinli, Seyma, Kilaru, Varun, Kessler, Ronald C., Kimbrel, Nathan A., Koenen, Karestan C., Kuan, Pei-Fen, Li, Kefeng, Logue, Mark W., Lori, Adriana, Luft, Benjamin J., Miller, Mark W., Naviaux, Jane C., Nugent, Nicole R., Qin, Xuejun, Ressler, Kerry J., Risbrough, Victoria B., Rutten, Bart P. F., Stein, Murray B., Ursano, Robert J., Vermetten, Eric, Vinkers, Christiaan H., Wang, Lin, Youssef, Nagy A., Uddin, Monica, Nievergelt, Caroline M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686485/
https://www.ncbi.nlm.nih.gov/pubmed/33235198
http://dx.doi.org/10.1038/s41467-020-19615-x

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