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Assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion

PURPOSE: To investigate platelet-to-lymphocyte ratio (PLR) in retinal vein occlusion (RVO) patients. METHODS: In this study, we retrospectively reviewed data of 32 patients with RVO (RVO group) and 32 age- and sex-matched participants without RVO (control group) between January 2017 and March 2019....

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Autores principales: Kurtul, Bengi Ece, Çakmak, Ayșe İdil, Elbeyli, Ahmet, Özarslan Özcan, Deniz, Özcan, Sait Coșkun, Cankurtaran, Veysel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686591/
https://www.ncbi.nlm.nih.gov/pubmed/33283155
http://dx.doi.org/10.1177/2515841420971949
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author Kurtul, Bengi Ece
Çakmak, Ayșe İdil
Elbeyli, Ahmet
Özarslan Özcan, Deniz
Özcan, Sait Coșkun
Cankurtaran, Veysel
author_facet Kurtul, Bengi Ece
Çakmak, Ayșe İdil
Elbeyli, Ahmet
Özarslan Özcan, Deniz
Özcan, Sait Coșkun
Cankurtaran, Veysel
author_sort Kurtul, Bengi Ece
collection PubMed
description PURPOSE: To investigate platelet-to-lymphocyte ratio (PLR) in retinal vein occlusion (RVO) patients. METHODS: In this study, we retrospectively reviewed data of 32 patients with RVO (RVO group) and 32 age- and sex-matched participants without RVO (control group) between January 2017 and March 2019. The PLR was determined by dividing the platelet count by the lymphocyte count. RESULTS: Age and gender were comparable between the groups (p = 0.204 and p = 0.800, respectively). PLR was significantly elevated in the RVO group compared with the control group (137 (113–164) vs 101 (86–129), p = 0.001)). In the receiver operator characteristics curve analysis, the optimal cut-off value of PLR for predicting RVO was 123, with 69% sensitivity and 72% specificity. CONCLUSION: We report that PLR are elevated in RVO, suggesting that PLR may be a useful marker for RVO.
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spelling pubmed-76865912020-12-03 Assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion Kurtul, Bengi Ece Çakmak, Ayșe İdil Elbeyli, Ahmet Özarslan Özcan, Deniz Özcan, Sait Coșkun Cankurtaran, Veysel Ther Adv Ophthalmol Original Research PURPOSE: To investigate platelet-to-lymphocyte ratio (PLR) in retinal vein occlusion (RVO) patients. METHODS: In this study, we retrospectively reviewed data of 32 patients with RVO (RVO group) and 32 age- and sex-matched participants without RVO (control group) between January 2017 and March 2019. The PLR was determined by dividing the platelet count by the lymphocyte count. RESULTS: Age and gender were comparable between the groups (p = 0.204 and p = 0.800, respectively). PLR was significantly elevated in the RVO group compared with the control group (137 (113–164) vs 101 (86–129), p = 0.001)). In the receiver operator characteristics curve analysis, the optimal cut-off value of PLR for predicting RVO was 123, with 69% sensitivity and 72% specificity. CONCLUSION: We report that PLR are elevated in RVO, suggesting that PLR may be a useful marker for RVO. SAGE Publications 2020-11-18 /pmc/articles/PMC7686591/ /pubmed/33283155 http://dx.doi.org/10.1177/2515841420971949 Text en © The Author(s), 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research
Kurtul, Bengi Ece
Çakmak, Ayșe İdil
Elbeyli, Ahmet
Özarslan Özcan, Deniz
Özcan, Sait Coșkun
Cankurtaran, Veysel
Assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion
title Assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion
title_full Assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion
title_fullStr Assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion
title_full_unstemmed Assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion
title_short Assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion
title_sort assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686591/
https://www.ncbi.nlm.nih.gov/pubmed/33283155
http://dx.doi.org/10.1177/2515841420971949
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