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Occult Talaromyces marneffei Infection Unveiled by the Novel Mp1p Antigen Detection Assay
Talaromyces marneffei causes fatal invasive mycosis in Southeast Asia. Diagnosis by culture has limited sensitivity and can result in treatment delay. We describe the use of a novel Mp1p enzyme immunoassay (EIA) to identify blood culture–negative talaromycosis, subsequently confirmed by bone marrow...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686654/ https://www.ncbi.nlm.nih.gov/pubmed/33269295 http://dx.doi.org/10.1093/ofid/ofaa502 |
| _version_ | 1783613373682810880 |
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| author | Ly, Vo Trieu Thanh, Nguyen Tat Thu, Nguyen Thi Mai Chan, Jasper Day, Jeremy N Perfect, John Nga, Cao Ngoc Vinh Chau, Nguyen Van Le, Thuy |
| author_facet | Ly, Vo Trieu Thanh, Nguyen Tat Thu, Nguyen Thi Mai Chan, Jasper Day, Jeremy N Perfect, John Nga, Cao Ngoc Vinh Chau, Nguyen Van Le, Thuy |
| author_sort | Ly, Vo Trieu |
| collection | PubMed |
| description | Talaromyces marneffei causes fatal invasive mycosis in Southeast Asia. Diagnosis by culture has limited sensitivity and can result in treatment delay. We describe the use of a novel Mp1p enzyme immunoassay (EIA) to identify blood culture–negative talaromycosis, subsequently confirmed by bone marrow cultures. This EIA has the potential to speed diagnosis, enabling early therapy initiation. |
| format | Online Article Text |
| id | pubmed-7686654 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Oxford University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-76866542020-12-01 Occult Talaromyces marneffei Infection Unveiled by the Novel Mp1p Antigen Detection Assay Ly, Vo Trieu Thanh, Nguyen Tat Thu, Nguyen Thi Mai Chan, Jasper Day, Jeremy N Perfect, John Nga, Cao Ngoc Vinh Chau, Nguyen Van Le, Thuy Open Forum Infect Dis Brief Reports Talaromyces marneffei causes fatal invasive mycosis in Southeast Asia. Diagnosis by culture has limited sensitivity and can result in treatment delay. We describe the use of a novel Mp1p enzyme immunoassay (EIA) to identify blood culture–negative talaromycosis, subsequently confirmed by bone marrow cultures. This EIA has the potential to speed diagnosis, enabling early therapy initiation. Oxford University Press 2020-10-19 /pmc/articles/PMC7686654/ /pubmed/33269295 http://dx.doi.org/10.1093/ofid/ofaa502 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Brief Reports Ly, Vo Trieu Thanh, Nguyen Tat Thu, Nguyen Thi Mai Chan, Jasper Day, Jeremy N Perfect, John Nga, Cao Ngoc Vinh Chau, Nguyen Van Le, Thuy Occult Talaromyces marneffei Infection Unveiled by the Novel Mp1p Antigen Detection Assay |
| title | Occult Talaromyces marneffei Infection Unveiled by the Novel Mp1p Antigen Detection Assay |
| title_full | Occult Talaromyces marneffei Infection Unveiled by the Novel Mp1p Antigen Detection Assay |
| title_fullStr | Occult Talaromyces marneffei Infection Unveiled by the Novel Mp1p Antigen Detection Assay |
| title_full_unstemmed | Occult Talaromyces marneffei Infection Unveiled by the Novel Mp1p Antigen Detection Assay |
| title_short | Occult Talaromyces marneffei Infection Unveiled by the Novel Mp1p Antigen Detection Assay |
| title_sort | occult talaromyces marneffei infection unveiled by the novel mp1p antigen detection assay |
| topic | Brief Reports |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686654/ https://www.ncbi.nlm.nih.gov/pubmed/33269295 http://dx.doi.org/10.1093/ofid/ofaa502 |
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