Genome-Wide Association Study Identifies Novel Colony Stimulating Factor 1 Locus Conferring Susceptibility to Cryptococcosis in Human Immunodeficiency Virus-Infected South Africans

BACKGROUND: Cryptococcus is the most common cause of meningitis in human immunodeficiency virus (HIV)-infected Africans. Despite universal exposure, only 5%–10% of patients with HIV/acquired immune deficiency syndrome and profound CD4(+) T-cell depletion develop disseminated cryptococcosis: host gen...

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Detalles Bibliográficos
Autores principales: Kannambath, Shichina, Jarvis, Joseph N, Wake, Rachel M, Longley, Nicky, Loyse, Angela, Matzaraki, Vicky, Aguirre-Gamboa, Raúl, Wijmenga, Cisca, Doyle, Ronan, Paximadis, Maria, Tiemessen, Caroline T, Kumar, Vinod, Pittman, Alan, Meintjes, Graeme, Harrison, Thomas S, Netea, Mihai G, Bicanic, Tihana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Major Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686661/
https://www.ncbi.nlm.nih.gov/pubmed/33269293
http://dx.doi.org/10.1093/ofid/ofaa489

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