Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain

CHD8 encodes a chromatin-remodeling factor and is one of the most recurrently mutated genes in individuals with autism spectrum disorder (ASD). Although we have recently shown that mice heterozygous for Chd8 mutation manifest myelination defects and ASD-like behaviors, the detailed mechanisms underl...

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Detalles Bibliográficos
Autores principales: Kawamura, Atsuki, Abe, Yoshifumi, Seki, Fumiko, Katayama, Yuta, Nishiyama, Masaaki, Takata, Norio, Tanaka, Kenji F., Okano, Hideyuki, Nakayama, Keiichi I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686671/
https://www.ncbi.nlm.nih.gov/pubmed/33228730
http://dx.doi.org/10.1186/s13041-020-00699-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686671/
https://www.ncbi.nlm.nih.gov/pubmed/33228730
http://dx.doi.org/10.1186/s13041-020-00699-x

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