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Molecular and cellular mechanisms of aging in hematopoietic stem cells and their niches

Aging drives the genetic and epigenetic changes that result in a decline in hematopoietic stem cell (HSC) functioning. Such changes lead to aging-related hematopoietic/immune impairments and hematopoietic disorders. Understanding how such changes are initiated and how they progress will help in the...

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Detalles Bibliográficos
Autores principales:	Zhang, Lei, Mack, Ryan, Breslin, Peter, Zhang, Jiwang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686726/ https://www.ncbi.nlm.nih.gov/pubmed/33228751 http://dx.doi.org/10.1186/s13045-020-00994-z

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