Roquin1 inhibits the proliferation of breast cancer cells by inducing G1/S cell cycle arrest via selectively destabilizing the mRNAs of cell cycle–promoting genes

BACKGROUND: Dysregulation of cell cycle progression is a common feature of human cancer cells; however, its mechanism remains unclear. This study aims to clarify the role and the underlying mechanisms of Roquin1 in cell cycle arrest in breast cancer. METHODS: Public cancer databases were analyzed to...

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Detalles Bibliográficos
Autores principales: Lu, Wenbao, Zhou, Meicen, Wang, Bing, Liu, Xueting, Li, Bingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686734/
https://www.ncbi.nlm.nih.gov/pubmed/33228782
http://dx.doi.org/10.1186/s13046-020-01766-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686734/
https://www.ncbi.nlm.nih.gov/pubmed/33228782
http://dx.doi.org/10.1186/s13046-020-01766-w

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