Cargando…

Roquin1 inhibits the proliferation of breast cancer cells by inducing G1/S cell cycle arrest via selectively destabilizing the mRNAs of cell cycle–promoting genes

BACKGROUND: Dysregulation of cell cycle progression is a common feature of human cancer cells; however, its mechanism remains unclear. This study aims to clarify the role and the underlying mechanisms of Roquin1 in cell cycle arrest in breast cancer. METHODS: Public cancer databases were analyzed to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Wenbao, Zhou, Meicen, Wang, Bing, Liu, Xueting, Li, Bingwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686734/ https://www.ncbi.nlm.nih.gov/pubmed/33228782 http://dx.doi.org/10.1186/s13046-020-01766-w

Ejemplares similares

TARBP2 promotes tumor angiogenesis and metastasis by destabilizing antiangiogenic factor mRNAs
por: Zhou, Meicen, et al.
Publicado: (2021)

Roquin2 suppresses breast cancer progression by inhibiting tumor angiogenesis via selectively destabilizing proangiogenic factors mRNA
por: Zhou, Meicen, et al.
Publicado: (2021)

Regnase-1 and Roquin regulate inflammatory mRNAs
por: Mino, Takashi, et al.
Publicado: (2015)

Roquin targets mRNAs in a 3′-UTR-specific manner by different modes of regulation
por: Essig, Katharina, et al.
Publicado: (2018)

Tectorigenin Inhibits Glioblastoma Proliferation by G0/G1 Cell Cycle Arrest
por: Yeh, Liang-Tsai, et al.
Publicado: (2020)

Raltitrexed Inhibits HepG2 Cell Proliferation via G(0)/G(1) Cell Cycle Arrest
por: Zhao, Hongwei, et al.
Publicado: (2016)

Downregulation of FTL decreases proliferation of malignant mesothelioma cells by inducing G(1) cell cycle arrest
por: Kambara, Takahiro, et al.
Publicado: (2022)

Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells
por: Hong, Bok Sil, et al.
Publicado: (2009)

Downregulation of FOXP1 Inhibits Cell Proliferation in Hepatocellular Carcinoma by Inducing G1/S Phase Cell Cycle Arrest
por: Wang, Xin, et al.
Publicado: (2016)

Neutrophil Suppresses Tumor Cell Proliferation via Fas /Fas Ligand Pathway Mediated Cell Cycle Arrested
por: Sun, Bingwei, et al.
Publicado: (2018)

A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin
por: Sgromo, Annamaria, et al.
Publicado: (2017)

Mitogen-Induced B-Cell Proliferation Activates Chk2-Dependent G1/S Cell Cycle Arrest
por: Nikitin, Pavel A., et al.
Publicado: (2014)

Knockdown of NANOG Reduces Cell Proliferation and Induces G0/G1 Cell Cycle Arrest in Human Adipose Stem Cells
por: Pitrone, Maria, et al.
Publicado: (2019)

G2/M cell cycle arrest in the life cycle of viruses
por: Davy, Clare, et al.
Publicado: (2007)

Small Intestine Inflammation in Roquin-Mutant and Roquin-Deficient Mice
por: Schaefer, Jeremy S., et al.
Publicado: (2013)

Molecular Mechanisms Underlying Yatein-Induced Cell-Cycle Arrest and Microtubule Destabilization in Human Lung Adenocarcinoma Cells
por: Ho, Shang-Tse, et al.
Publicado: (2019)

Bunyaviral cap-snatching vs. decapping: Recycling cell cycle mRNAs
por: Hopkins, Kaycie, et al.
Publicado: (2013)

Stress Granules Contain Rbfox2 with Cell Cycle-related mRNAs
por: Park, Chungoo, et al.
Publicado: (2017)

Overexpression of LASS2 inhibits proliferation and causes G0/G1 cell cycle arrest in papillary thyroid cancer
por: Zeng, Feng, et al.
Publicado: (2018)

Casticin induces apoptosis and G0/G1 cell cycle arrest in gallbladder cancer cells
por: Song, Xiao-ling, et al.
Publicado: (2017)

Hfq Globally Binds and Destabilizes sRNAs and mRNAs in Yersinia pestis
por: Han, Yanping, et al.
Publicado: (2019)

Panduratin A Inhibits Cell Proliferation by Inducing G0/G1 Phase Cell Cycle Arrest and Induces Apoptosis in Breast Cancer Cells
por: Liu, Qiuming, et al.
Publicado: (2018)

CMPD1 inhibited human gastric cancer cell proliferation by inducing apoptosis and G2/M cell cycle arrest
por: Li, Yu, et al.
Publicado: (2018)

CDC25A inhibition suppresses cell proliferation and induces G(1)/S‑phase cell cycle arrest in nasopharyngeal carcinoma
por: Wang, Bin, et al.
Publicado: (2023)

Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest
por: Ujiki, Michael B, et al.
Publicado: (2006)

Tamarix articulata Inhibits Cell Proliferation, Promotes Cell Death Mechanisms and Triggers G(0)/G(1) Cell Cycle Arrest in Hepatocellular Carcinoma Cells
por: Alnuqaydan, Abdullah M., et al.
Publicado: (2021)

ROQUIN/RC3H1 Alterations Are Not Found in Angioimmunoblastic T-Cell Lymphoma
por: Auguste, Tiphanie, et al.
Publicado: (2013)

Flubendazole inhibits glioma proliferation by G2/M cell cycle arrest and pro-apoptosis
por: Zhou, Xumin, et al.
Publicado: (2018)

No defect in G1/S cell cycle arrest in irradiated Li-Fraumeni lymphoblastoid cell lines.
por: Williams, K. J., et al.
Publicado: (1996)

Eupatilin inhibits glioma proliferation, migration, and invasion by arresting cell cycle at G1/S phase and disrupting the cytoskeletal structure
por: Fei, Xiaowei, et al.
Publicado: (2019)

Single-molecule imaging reveals translation-dependent destabilization of mRNAs
por: Dave, Pratik, et al.
Publicado: (2023)

Ursolic acid benzaldehyde chalcone, leads to inhibition of cell proliferation and arrests cycle in G1/G0 phase in colon cancer
por: Zhuang, Xinying, et al.
Publicado: (2018)

Moxidectin inhibits glioma cell viability by inducing G0/G1 cell cycle arrest and apoptosis
por: Song, Dandan, et al.
Publicado: (2018)

Newcastle disease virus induces G(0)/G(1) cell cycle arrest in asynchronously growing cells
por: Wang, Yan, et al.
Publicado: (2018)

Hematopoietic not systemic impairment of Roquin expression accounts for intestinal inflammation in Roquin-deficient mice
por: Montufar-Solis, Dina, et al.
Publicado: (2014)

Relief from nitrogen starvation triggers transient destabilization of glycolytic mRNAs in Saccharomyces cerevisiae cells
por: Tesnière, Catherine, et al.
Publicado: (2018)

Overexpression of RNA-binding protein CELF1 prevents apoptosis and destabilizes pro-apoptotic mRNAs in oral cancer cells
por: Talwar, Sudha, et al.
Publicado: (2013)

TBX3 knockdown suppresses the proliferation of hypopharyngeal carcinoma FaDu cells by inducing G1/S cell cycle arrest and apoptosis
por: Huang, Yongjiu, et al.
Publicado: (2020)

Characterization of specific HHV-6 and cell cycle genes implicated in virus-mediated G1/S cell-cycle arrest of glial precursors
por: Mock, David J, et al.
Publicado: (2006)

Cell cycle-related lncRNAs and mRNAs in osteoarthritis chondrocytes in a Northwest Chinese Han Population
por: Zhang, Feng’e, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_pbljedoukk84dlg8as3s9mhddf