Nicotinamide, a vitamin B3 ameliorates depressive behaviors independent of SIRT1 activity in mice

Sirtuin 1 (SIRT1), is a nicotinamide adenine dinucleotide (NAD(+))-dependent protein deacetylase and a candidate gene for depression. Nicotinamide (NAM), a form of vitamin B3, is reported as a potential inhibitor of SIRT1. Our previous study found that the 24-h-restraint stress could induce long-ter...

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Detalles Bibliográficos
Autores principales: Liu, Zhuxi, Li, Caiqin, Fan, Xuelian, Kuang, Yifang, Zhang, Xu, Chen, Lei, Song, Jinjing, Zhou, Ying, Takahashi, Eiki, He, Guang, Li, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686777/
https://www.ncbi.nlm.nih.gov/pubmed/33228716
http://dx.doi.org/10.1186/s13041-020-00703-4

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