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Resveratrol Inhibits Lipopolysaccharide-Induced Extracellular Matrix Accumulation and Inflammation in Rat Glomerular Mesangial Cells by SphK1/S1P2/NF-κB Pathway

PURPOSE: Chronic inflammation plays a key role in the pathogenesis of various diseases such as diabetic nephropathy (DN). Resveratrol (RSV), a natural polyphenol, has been proven to have renoprotective effects. In this study, we used a lipopolysaccharide (LPS)-induced rat glomerular mesangial cells...

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Detalles Bibliográficos
Autores principales: Gong, Wenyan, Li, Jie, Chen, Wenying, Feng, Fuzhen, Deng, Yanhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686914/
https://www.ncbi.nlm.nih.gov/pubmed/33262625
http://dx.doi.org/10.2147/DMSO.S278267

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